Imaging
technology : imaging
Imaging and diagnosis
Our platform technology incorporates a unique luminescent fusion protein designed to enable cancer diagnosis, staging and monitoring. This protein is a combination of two proteins from glowing sea pansies and jellyfish. After the virus finds and enters a tumor, it begins to replicate, proportionally emitting light throughout the viral amplification process. In preclinical testing, this has enabled accurate, non-invasive detection and imaging of cancer progression/regression in real time, as well as microscopic imaging of tumor biopsies at tissue or cellular levels.
Clinical trials of our flagship product GL-ONC1 may utilize this technology to supplement safety and efficacy evaluations. Ultimately, the bioluminescent capabilities of GL-ONC1 may be replaced with novel or existing clinical imaging technologies. GL-ONC1 could also become a powerful tool for cancer staging or intraoperative imaging.